Synthesis of Methylenebicyclo[3.2.1]octanol by a Sm(II)-Induced 1,2-Rearrangement Reaction with Ring Expansion of Methylenebicyclo[4.2.0]octanone
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https://figshare.com/articles/dataset/Synthesis_of_Methylene_bicyclo_3_2_1_octanol_by_a_Sm_II_-Induced_1_2-Rearrangement_Reaction_with_Ring_Expansion_of_Methylene_bicyclo_4_2_0_octanone/5155690
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资源简介：
Direct conversion
of methylenebicyclo[4.2.0]octanone
to methylenebicyclo[3.2.1]octanol by a Sm(II)-induced
1,2-rearrangement with ring expansion of the methylenecyclobutane
is described. Three conditions were optimized to allow the adaptation
of this approach to various substrates. A rearrangement mechanism
is proposed involving the generation of a ketyl radical and cyclopentanation
by ketyl–olefin cyclization, followed by radical fragmentation
and subsequent protonation.
创建时间：
2017-06-29
