Thyroid hormone receptor beta (THRβ1) is the major regulator of T3 action in human iPSC-derived hepatocytes

To investigate the role of THRβ1 action in human iPSC-derived hepatocytes. We then performed gene expression profiling analysis using data obtained from RNA-seq of WT and THRBKO human iPSCs-derived hepatocytes in presence and absence of T3. Comparative gene expression profiling analysis of RNA-seq data for BU3-10-CR2 cells (WT) and its KO derivative (THRBKO) in presence and absence of T3.