Epigenetic modifiers are promising targets to improve therapies in patients with cancer. Targeting the methyltransferase DOT1L with small molecule inhibitors has shown promising effects on the control
Imaging data across Embryonic Stages from Figure S7 of "Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila" by Fitz-James et al.
The chromatin landscape of human mast cells is extensively reorganized upon FceRI crosslinking Overall design: Human mast cells were generated from peripheral blood-derived CD34+ cells with recombinan