five

Cell-type-specific GReX models trained on ROSMAP by scTWAS

收藏
Figshare2026-02-13 更新2026-04-28 收录
下载链接:
https://figshare.com/articles/dataset/Cell-type-specific_GReX_models_trained_on_ROSMAP_by_scTWAS/31329139
下载链接
链接失效反馈
官方服务:
资源简介:
scTWAS_ROSMAP_celltypes_wgt.tar contains the significant cell-type-specific GReX weights (in FUSION format) on six major cell types identified in our analysis.scTWAS_ROSMAP_subtypes_wgt.tar contains the significant cell-subtype-specific GReX weights (in FUSION format) on 70 cell subtypes identified in our analysis. Five cell subtypes did not yield any significant gene-expression prediction models and are therefore not included in this release.* Only genes whose prediction p-values, evaluated under a cross-validation framework in Stage 1, passed the Bonferroni correction (These datasets contain weight files (formatted as *_scTWAS.wgt.RDat) generated via the scTWAS framework. Users should note the following specifications regarding the internal variables:wgt.matrix: Contains 10 columns representing 10 iterations of scTWAS. The last column was used as the final weight for all analyses. The SNP identifiers in wgt.matrix are formatted as chromosome:position, where the position corresponds to the GRCh37 genome build.Please disregard hsq and hsq.pv; these are not intended outputs of the scTWAS algorithm and should not be used for interpretation.
创建时间:
2026-02-13
5,000+
优质数据集
54 个
任务类型
进入经典数据集
二维码
社区交流群

面向社区/商业的数据集话题

二维码
科研交流群

面向高校/科研机构的开源数据集话题

数据驱动未来

携手共赢发展

商业合作