E-GEOD-1919

NIAID Data Ecosystem2026-05-02 收录

类风湿关节炎分子病理

滑膜转录组分析

数据链接：

https://www.omicsdi.org/dataset/atlas-experiments/E-GEOD-1919 数据链接链接失效反馈

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资源简介：

Transcription profiling of human synovial samples from patients with osteoarthritis, rheumatoid arthritis vs controls treated with various drug regimes to characterise RA at the molecular level and to uncover key pathomechanisms

创建时间：

2025-01-24

Comprehensive transcriptome analysis of synovium and peripheral blood reveals major disease heterogeneity early in the RA disease process prior to therapeutic intervention. Comprehensive transcriptome analysis of synovium and peripheral blood reveals major disease heterogeneity early in the RA disease process prior to therapeutic intervention

类风湿关节炎分型

滑膜转录组分析

We report the first comparative analysis between histology, RNA-seq of synovium and matched peripheral blood, and clinico-radiological parameters in early rheumatoid arthritis (RA). Using a novel modu

NIAID Data Ecosystem60

Identification of differentially-expressed key biomarkers in the synovium of osteoarthritic patients using mRNA sequencing and bioinformatics analyses

关节炎生物标志物

滑膜转录组分析

The aim of the study was to identify differentially-expressed gene (DEG) biomarkers in the synovium of OA patients using mRNA sequencing data, bioinformatics analyses, and histochemistry/ immunohistoc

NIAID Data Ecosystem40

Sexual dimorphism of the synovial transcriptome underpins greater PTOA disease severity in male mice following joint injury

创伤（医学与心理）

滑膜转录组分析

Osteoarthritis (OA) is a disease with sex-dependent prevalence and severity in both human and animal models. We sought to elucidate sex differences in synovitis, mechanical sensitization, structural d

NIAID Data Ecosystem20

Epigenetic regulator UHRF1 suppressively organize multiple pathogenesis in rheumatoid arthritis [MBD-seq]

类风湿关节炎分子病理

表观遗传调控

Rheumatoid arthritis (RA) is characterized by chronic synovial inflammation with aberrant epigenetic alterations, leading joint destruction. However, epigenetic regulatory mechanisms underlying RA pat

NIAID Data Ecosystem50

Pathway gene ontology analysis of genes significantly up-regulated in IL17A + /CD21L + and IL17A - /CD21L - rheumatoid synovia.

类风湿关节炎分子病理

基因通路分析

Pathway gene ontology analysis of genes significantly up-regulated in IL17A+/CD21L+ and IL17A-/CD21L- rheumatoid synovia.

NIAID Data Ecosystem30