A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation.

ChEBI2014-03-04 更新2026-07-21 收录

粒细胞分化

SLPI分子机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53353 数据链接链接失效反馈

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资源简介：

A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation.

创建时间：

2014-03-04

Genome-wide analysis of histone modifications during neutrophilic granulopoiesis following ELF-MF exposure. Homo sapiens

表观遗传调控

粒细胞分化

To address whether ELF-MF influences the epigenetic landscape in differentiating haematopoietic cells, we performed an in vitro haematopoietic differentiation under powerline-simulating ELF-MF exposur

NIAID Data Ecosystem110

Temporal expression profile of granulocytic differentiation of primary CD34+ cells cultured under 20% O2 levels. Homo sapiens

粒细胞分化

时序转录组学

Little is known about the global transcriptional program underlying granulocytic (G) commitment, differentiation and maturation. Using DNA microarrays and Q-RT-PCR, we examined the transcriptional pro

NIAID Data Ecosystem60

A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation.. Homo sapiens

粒细胞分化

SLPI功能研究

Expression data from CD34+ hematopoietic cells transduced with control or anti-SLPI shRNA, serum starved and treated with G-CSF. Overall design: CD34+ hematopoietic cells were isolated from the bone m

NIAID Data Ecosystem50

Gene expression profiles during the process of differentiation of HL-60 AK2 hetero-knockout clone #5 cells into neutrophils [HL60AK2KO_clone5]. Gene expression profiles during the process of differentiation of HL-60 AK2 hetero-knockout clone #5 cells into neutrophils [HL60AK2KO_clone5]

粒细胞分化

基因表达谱分析

To investigate the changes in gene expression during the process of differentiation into neutrophils and to evaluate the effect of Ak2 hetero-knockout in the process, microarray analysis was performed

NIAID Data Ecosystem80

Nuclear Morphology is Instructed by the Loop Extrusion Program [RNA-seq]. Nuclear Morphology is Instructed by the Loop Extrusion Program [RNA-seq]

核转运调控

粒细胞分化

More than a century ago Metchnikoff defined neutrophils as small amoeboid-like cells that harbored peculiar polymorphonuclear structures. While since these early studies much has been learned about ne

NIAID Data Ecosystem50

A lack of secretory leukocyte protease inhibitor (SLPI) causes defects in granulocytic differentiation.

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