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Effect of LSD1 inhibition on differentiating C2C12 myoblasts

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE86524
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Analysis of differentiating C2C12 myoblasts treated with two LSD1 specific inhibitors. We found LSD1 is an important regulator of oxidative phenotypes in skeletal muscle cells. Results provide insight into the molecular mechanisms underlying roles of LSD1 in myocytes. C2C12 cells were induced to differentiate with LSD1 inhibitors, tranylcypromine (TC) or S2101, or vehicle control. 48 hours later total RNAs were isolated and subjected with microarray analysis.
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2019-02-11
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