Profiling of lung tumor-infiltrating CD8 T cells according to their expression status of CD39
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE113588
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资源简介：
Human tumors are infiltrated by various immune cells, including CD8 T cells. CD8 T cells express unique receptors that can recognize peptides at the host’s cells, including tumor cells. After probing the antigen specificity of ex-vivo tumor-infiltrating CD8 T cells from human tumors, we hypothesized that expression of CD39 was correlated with tumor-specificity. The present experiment aims at better characterizing ex-vivo CD39+ vs CD39- CD8 T cells. CD39- and CD39+ CD8 T cells were FACS sorted from 8 fresh tumor samples and their RNA extracted for transcriptomic profiling.
创建时间：
2019-03-21
