Crystal Structure of EGFR-T790M/V948R in Complex with Osimertinib and EAI045
收藏Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystal Structure of EGFR-T790M/V948R in Complex with Osimertinib and EAI045 Descriptor: (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, SULFATE ION, ... Authors: Niggenaber, J, Mueller, M.P, Rauh, D. Deposit date: 2020-05-25 Release date: 2020-11-11 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Complex Crystal Structures of EGFR with Third-Generation Kinase Inhibitors and Simultaneously Bound Allosteric Ligands. Acs Med.Chem.Lett., 11, 2020
创建时间:
2020-05-25



