官方服务：
资源简介：
Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice
应用场景：
创建时间：
2014-10-27
相关数据集
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation. Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation
Many neurodegenerative diseases are characterized by the presence of intracellular protein aggregates resulting in alterations in autophagy. However, the consequences of impaired autophagy on neuronal
NIAID Data Ecosystem70
White adipose tissue browning in the R6/2 mouse model of Huntington's disease
We investigated gene expression signatures in subcutaneous inguinal adipose tissue obtained from wild type and R6/2 mice with the aim to identify gene expression changes and signalling pathway alterat
NIAID Data Ecosystem70
Analysis of Proteolytic Processes and Enzymatic Activities in the Generation of Huntingtin N-Terminal Fragments in an HEK293 Cell Model
BackgroundN-terminal fragments of mutant huntingtin (htt) that terminate between residues 90–115, termed cleavage product A or 1 (cp-A/1), form intracellular and intranuclear inclusion bodies in the b
Figshare2016-01-19 更新40
ER_RNASeq_LAQ5MGvsCONTROL.xlsx
The RNASeq Raw data related to the article of "Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease" Figure 4
NIAID Data Ecosystem70
Supplementary Information Patra et al.
Supplementary material to the article "A genome wide dosage suppressor network reveals genetic robustness and a novel mechanism for Huntington’s disease", by Patra et al. o Supplementary Figures S1-S8
Figshare2016-01-18 更新50
