Atlas of Gene Expression at Microanatomical Resolution of the Submandibular Salivary Gland

The goal of this study was to generate a spatio-temporal atlas of gene expression in the developing salivary gland. This will allow us to identify changes in gene expression that may result in the formation of the different domains of the salivary gland. At least 4 microarrays per location per time point were collected. The originating samples are rather small, so many clefts, ducts and buds had to be pooled to generate enough RNA for hybridization.