Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand
收藏Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/6fsy
下载链接
链接失效反馈官方服务：
资源简介：
Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand Descriptor: 1,2-ETHANEDIOL, 3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[(~{R})-oxidanyl(pyridin-3-yl)methyl]phenol, Bromodomain-containing protein 4 Authors: Filippakopoulos, P, Picaud, S, Conway, S.J, Pike, A.C.W, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Structural Genomics Consortium (SGC) Deposit date: 2018-02-20 Release date: 2018-04-18 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.34 Å) Cite: BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability. Bioorg.Med.Chem., 26, 2018
创建时间：
2018-02-20
