The host response to influenza virus infection

In this study, we performed a cross-species gene expression study of the peripheral blood from the Collaborative Cross (CC) mouse population after Influenza virus (IV). Blood was taken for RNA isolation at different time points after virus infection (day 3, 5 and 8) and mock infection (day 3 post sterile phosphate-buffered saline infection). Body weight was measured until the day of sample collection. For every treatment and day post infection (pi), 3-5 mice per CC strain were analyzed.