Folding Directed N-Oxidation of Oligopyridine−Dicarboxamide Strands and Hybridization of Oxidized Oligomers

Folding of oligopyridine−dicarboxamides into helices inhibits the N-oxidation of pyridine rings central in the sequence and also much enhances the N-oxidation of pyridine rings peripheral in the sequence. Oligomers N-oxidized at their terminal position show an increased ability to hybridize into double helices.