Gene expression profiling in mice with the depletion of prolyl hydroxylase domain proteins in endothelial cells. Gene expression profiling in mice with the depletion of prolyl hydroxylase domain proteins in endothelial cells

To evaluate gene expression changes in response to prolyl hydroxylase domain protein 2 and 3 (PHD2/3) depletion in endothelial cells, we performed mRNA-sequencing analysis with heart samples isolated from PHD2/3 endothelial knockout mice and their littermate control wild type mice. Overall design: Whole hearts were collected from the PHD2/3 endothelial knockout mice and their littermate control wild type mice at P12.