BALF cell profiles and organ weights in Ganetespib treated mice.
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https://figshare.com/articles/dataset/_BALF_cell_profiles_and_organ_weights_in_Ganetespib_treated_mice_/1293803
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Groups of male BALB/c mice were treated with vehicle or GIB at the indicated doses. No LPS denotes no LPS treatment. LPS denotes LPS challenge (10µg/mouse, tn). Cells. Macrophage subpopulations were designated according to expression of CD11b vs CD11c as follows: CD11chiCD11b- = resident macrophages, CD11chiCD11bhi = intermediate macrophages, CD11cloCD11bhi = monocytic macrophages. Dendritic cells (DCs) were defined as MHCII bright CD11c+ cells. FACS data are from pooled samples and are shown as mean ± SEM of triplicate replicates. NK cells were defined as CD45+CD19-γδTCR-TCRβ-CD49b+ and NKT cells as CD45+CD19-γδTCR-TCRβ+CD49b+. Data are shown as mean ± SEM for n = 8/group (naïve; n = 4). Organ weight. Mice weighed approximately 22 g prior to treatment and there was no significant difference in basal weight between groups.
BALF cell profiles and organ weights in Ganetespib treated mice.
创建时间：
2015-01-23
