The effect of knock-down of neuroblastoma associated lncRNA on transcriptome. Homo sapiens
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As part of functional characterization of neuroblastoma associated lncRNA HOXD-AS1, we performed its knock-down in neuroblastoma cell line SH-SY5Y, which resulted in modulation of expression levels of a set of genes involved in angiogenesis and inflammation, the hallmarks of metastatic cancer. Overall design: SH-SY5Y cells were transfected with non-targeting siRNA control and two siRNAs targeting lncRNA HOXD-AS1. Two days after transfection total RNA was isolated and hybridized to microarray, each sample was done in four replicas.
创建时间：
2012-09-07
