HIV-1 reverse transcriptase with aminopyrimidine inhibitor 2
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HIV-1 reverse transcriptase with aminopyrimidine inhibitor 2 Descriptor: 4-(4-{[4-(4-cyano-2,6-dimethylphenoxy)pyrimidin-2-yl]amino}piperidin-1-yl)benzenesulfonamide, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... Authors: Harris, S.F, Villasenor, A.G. Deposit date: 2010-06-03 Release date: 2010-08-18 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Discovery of piperidin-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-benzyl derivatives with broad potency against resistant mutant viruses. Bioorg.Med.Chem.Lett., 20, 2010
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2010-06-03
