Expression profiling of murine MYCN-driven neuroblastomas from LSL-MYCN; Dbh-iCre mice.. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA222324
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资源简介：
Amplification of MYCN is the most prominent genetic marker of high-stage neuroblastoma, a childhood tumor originating from the neural crest. We generated a transgenic mouse with Cre-conditional induction of MYCN in dopamine beta hydroxylase expressing cells that develops murine neuroblastomas. Overall design: The expression profiles of six tumors from adrenals and two tumors from superial cervical gangliae were compared to three non-malignant adrenals from wildtype mice. These profiles of adrenals have been previously described (Molenaar et al., Nature Genetics 2012). Wild type samples are accessible at the AMC webpage: http://hgserver1.amc.nl/cgi-bin/r2/main.cgi, and accessible for registered users.
创建时间：
2013-09-30
