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Notum_Inhibitor ARUK3000223

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Protein Data Bank Japan2024-11-06 更新2026-04-19 收录
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Notum_Inhibitor ARUK3000223 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, Palmitoleoyl-protein carboxylesterase NOTUM, ... Authors: Ruza, R, Zhao, Y, Fish, P, Jones, E.Y. Deposit date: 2021-08-26 Release date: 2022-09-07 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit. J.Med.Chem., 65, 2022
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2021-08-26
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