FAIRsharing record for: Minimum Information Model for tolAPC

This FAIRsharing record describes: The minimum information model for tolAPC (MITAP) guideline is an initiative of members of the tolAPC field to provide a reporting framework that will make differences and similarities between tolAPC products transparent. Cellular therapies with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation. The methodologies for generating tolAPC vary greatly between different laboratories, making it difficult to compare data from different studies; thus constituting a major hurdle for the development of standardised tolAPC therapeutic products. MITAP constitutes a first but important step towards the production of standardised and reproducible tolAPC for clinical application.