Straightforward Assembly of the Octahydroisoquinoline Core of Morphinan Alkaloids
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https://figshare.com/articles/dataset/Straightforward_Assembly_of_the_Octahydroisoquinoline_Core_of_Morphinan_Alkaloids/2767939
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资源简介:
The octahydroisoquinoline core of morphinan was assembled starting from readily available arylcyclohexadienes. Three different approaches were developed, including a metal- and an acid-mediated Mannich type process and an anionic-mediated cyclization. All provided the desired motif as a single diastereomer having a C9−C13−C14 trans−cis relative configuration.
创建时间:
2010-05-21



