Association results for Type 2 diabetes in Han Chinese.

aSNPs are arranged in order of decreasing P value under best statistical model in Stage 1.
bNeighboring SNPs also significantly associated with T2D.
cPreviously reported SNP associated with T2D 28, 29 and validated in our study.
*Empirical P value <106 after 108 permutations.
Stage 1(Genome scan) included 995 cases and 894 controls. Stage 2 (replication stage) included 1,803 cases and 1,473 controls. Alleles were indexed to the forward strand of NCBI Build 36. P value (trend), P value (PC), P value (permutation), and P value (meta) represent P values of trend test, principal component analysis using EIGENSTRAT, permutation, and meta-analysis using Fisher's method, respectively.
Risk allele, allele with higher frequency in cases compared to controls; RAF (T2D) and RAF (NC), risk allele frequencies in cases and controls, respectively; and OR, odds ratio for risk allele.