Summary of protein and protein interface counts in FLIPdb.

* Proteins chains are common to multiple sub-categories though the interfaces are distinct. ‡ Interfaces are constructed from existing FLIPs through coordinate transformations arising from the symmetry of the source X-ray crystal structure (XFunCs). FLIPdb contains 160 interfaces in 94 structures involving 219 individual protein chains. These interfaces have been assigned to FLIP or FunC functional categories and 9 functional sub-categories based on a review of the literature (see Supplement Table S1). Due to the reuse of some chains, the totals represented in the first two columns do not sum across sub-categories.