mRNA expression profiling of nasopharyngeal carcinoma cell line HONE1 upon ARNTL2 knockdown [RNA-seq]

Abnormal expression of circadian genes is known to be engage in tumor initiation and progression through disrupting rhythms of cellular processes. Here, we determined a significant role of the core circadian gene ARNTL2 in nasopharyngeal carcinoma metastasis. To further investigate the underlying mechanism of ARNTL2 in nasopharyngeal carcinoma, High-throughput RNA sequencing was performed in ARNTL2-knockdown HONE1 cell. Overall design: High-throughput RNA sequencing analysis was performed in human nasopharyngeal carcinoma cell line HONE1 transiently transfected with siARNTL2 or control siRNA.