Structure of human MTH1 in complex with TH287
收藏Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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Structure of human MTH1 in complex with TH287 Descriptor: 6-(2,3-dichlorophenyl)-N~4~-methylpyrimidine-2,4-diamine, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION Authors: Berntsson, R.P.-A, Jemth, A, Gustafsson, R, Svensson, L.M, Helleday, T, Stenmark, P. Deposit date: 2013-10-04 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature, 508, 2014
创建时间：
2013-10-04
