MYCN, an oncogene implicated in hepatocellular carcinoma (HCC), is predominantly expressed in cancer stem-like HCC cells. It drives tumorigenicity, metastasis, and therapeutic resistance. In this stud
Former studies demonstrated that the cembranoid type diterpenes in tobacco has a good antimicrobial, antitumor and neuroprotective activity. Hepatocellular carcinoma has been the world's second larges