Additional file 3 of Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes

ML tree of arrestins (depicted in Fig. 4). Starting information for tree reconstruction was an alignment of arrestins investigated in this study, for which sequence information was close to complete. Sequences derived from genomic annotations were substituted by sequences with experimental evidence available if these were more complete. The tree was constructed using PhyML from the amino acid sequences of arrestin paralogs from an alignment of nucleotide sequences aligned with MACSE (model JTT+G+I with Îą 1.04, p-invariable 0.05, 200x bootstrapping). The tree can be visualized with a tree viewer, e.g. Dendroscope [115]. (NW 1340 kb)