Transcriptomics of M0 macrophages treated with PTEN

While naive BMDMs without further treatment are referred to as M0-like macrophages, which can be polarized to either M1-like or M2-like macrophages,To assess the consequence of PTEN binding on macrophages, we profiled the global transcriptome of M0-like BMDMs with and without PTEN treatment. Overall design: Bone marrow-derived naive macrophages (M0 BMDMs) isolated from mice with and without treatment by 100 ng/mL PTEN for 24 h were subjected to RNA-seq.