Definition of adverse events.
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Abbreviations: ULN, upper limit of normal; AST, aspartate aminotransferase; ALT, alanine aminotransferase; CK, creatinine phosphokinase.
*Modified from Bellomo et al. 2004 [30].
†Criteria used in Klepper MJ and Covert B. 2010 [31].
‡Criteria used in Guidance of FDA. 2009 [32]. Increase of one or both of AST and ALT was counted as one event.
§Criteria used in Pasternak RC et al. 2002 [33].
创建时间:
2014-05-08



