Cryo-EM structure of ozanimod -bound Sphingosine-1-phosphate receptor 1 in complex with Gi protein
收藏Protein Data Bank Japan2025-06-18 更新2026-03-21 收录
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Cryo-EM structure of ozanimod -bound Sphingosine-1-phosphate receptor 1 in complex with Gi protein Descriptor: 5-[3-[(1~{S})-1-(2-hydroxyethylamino)-2,3-dihydro-1~{H}-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxy-benzenecarbonitrile, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... Authors: Yuan, Y, Jia, G.W, Su, Z.M, Shao, Z.H. Deposit date: 2021-05-24 Release date: 2021-09-29 Last modified: 2025-06-18 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: Structures of signaling complexes of lipid receptors S1PR1 and S1PR5 reveal mechanisms of activation and drug recognition. Cell Res., 31, 2021
创建时间:
2021-05-24



