Proteolytic processing of CD99
收藏NIAID Data Ecosystem2026-03-10 收录
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https://www.omicsdi.org/dataset/pride/PXD005428
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资源简介：
The adhesion molecule CD99 is essential for transendothelial migration (TEM) of leukocytes. Here we demonstrate by biochemical and cellular assays that CD99 undergoes ectodomain shedding by the metalloprotease meprin β and subsequent intramembrane proteolysis by γ-secretase. The cleavage site in CD99 was identified by mass spectrometry within an acidic region highly conserved through different vertebrate species.
创建时间：
2017-01-02
