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mTAIL-seq reveals dynamic poly(A) tail regulation in oocyte-to-embryo development

ChEBI2016-08-01 更新2026-07-12 收录

胚胎发育转录后调控

mTAIL-seq测序技术

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-83732 数据链接链接失效反馈

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资源简介：

mTAIL-seq reveals dynamic poly(A) tail regulation in oocyte-to-embryo development

应用场景：

创建时间：

2016-08-01

胚胎发育转录后调控

mRNA稳定性预测建模

Post-transcriptional regulation plays a crucial role in shaping gene expression. During the Maternal-to-Zygotic Transition (MZT), thousands of maternal transcripts are regulated, however, how differen

NIAID Data Ecosystem30

Pumilio regulates mRNA decay during the late maternal-to-zygotic transition in Drosophila melanogaster. Drosophila melanogaster

胚胎发育转录后调控

RNA结合蛋白功能

Pumilio (PUM) is a Drosophila member of a conserved family of sequence-specific RNA-binding proteins that have been shown to regulate mRNA stability and/or translation in a variety of organisms. PUM h

NIAID Data Ecosystem10

Underlying data for Figs 5 and S9.

胚胎发育转录后调控

母源mRNA降解机制

The translational repressor Nanos (Nos) regulates a single target, maternal hunchback (hb) mRNA, to govern abdominal segmentation in the early Drosophila embryo. Nos is recruited to sites in the 3′ UT

Figshare2024-10-14 更新00

miR-309-dependent unstable maternal mRNAs are stabilized in smaug mutants

母源性mRNA稳定性调控

胚胎发育转录后调控

miR-309-dependent unstable maternal mRNAs are stabilized in smaug mutants

ChEBI2010-06-19 更新10

mRNP reassembly triggers selective mRNA decay to drive rapid embryonic morphogenesis

胚胎发育转录后调控

细胞命运决定机制

Within a few hours of successful implantation, the mammalian embryo undergoes rapid morphological progression coupled with cell fate commitment. We show that the coordination and correct timing of the

NIAID Data Ecosystem00

mTAIL-seq reveals dynamic poly(A) tail regulation in oocyte-to-embryo development

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