Genetic modifiers of Duchenne muscular dystrophy in Chinese patients-Supplementary Material
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https://figshare.com/articles/dataset/Genetic_modifiers_of_Duchenne_muscular_dystrophy_in_Chinese_patients-Supplementary_Material/12421064
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We genotyped <i>LTBP4</i> haplotypes and the<i> SPP1</i> promoter SNPs rs28357094,
rs11730582, and rs17524488 in 326 patients registered in the neuromuscular
database of The First Affiliated Hospital of Sun Yat-sen University.
Kaplan-Meier curves and log-rank tests were used to estimate and compare median
age at loss of ambulation, while Cox proportional hazard regression models were
used as to analyze the effects of glucocorticoids treatments,
<i>DMD</i> genotype, and <i>SPP1</i>/<i>LTBP4</i>
SNPs on loss of ambulation.This
study was approved by the ICE for Clinical Research and Animal Trial at First
Affiliated Hospital of Sun Yat-sen University, and informed consent was
obtained from each included patient prior to the survey.
提供机构:
figshare
创建时间:
2020-06-04



