AtNAA50 behaviour in the core NatA complex

In eukaryotes, the N-terminal acetylation (NTA) is one of the most frequent protein modifications. In many organisms, and especially in plants, its biological function remains a mystery. In Arabidopsis thaliana, a large part of the proteome acetylation is catalyzed co-translationally by the action of the core NatA complex, which consitst of NAA10 and NAA15, respectively the catalytic and ribosome-anchoring subunits. This complex interacts with the NAA50 protein (NatE), which also has an N-acetyltransferase in organisms such as human and fruit fly. This project focuses on the effect of AtNAA50 knockouts on the activity of the essential NatA complex.