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m6A methyltransferase Mettl3 is essential for neuronal homeostasis and sleep via modulating Npy in mice

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To unravel the underlying mechanisms how neuronal Mettl3 loss induces the activation of microglia, we performed RNA-sequencing (RNA-seq) with the thalamic tissues of 2- and 4-month-old Ctrl and cKO mice, respectively. we performed bulk RNA sequencing (RNA-seq) with both ctrl and cKO mice brain in 2 month and 4 month to reveals the altered gene expression relating to microglia

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