Mouse colon expression in wild type and STAT5b deficient mice

Regulation of epithelial barrier function is dependent upon precise control of cell survival and activation of inflammatory pathways in response to the enteric flora. These experiments tested differential colon gene expression relative to these pathways in wild type and STAT5b deficient mice. Keywords: Single time point in wild type and STAT5b deficient mice. Colon RNA was isolated from adult wild type and STAT5b deficient mice.上皮屏障功能的调控，依赖于对细胞存活的精准调控，以及响应肠道菌群的炎症通路激活过程。本研究针对上述通路，分析了野生型与信号转导与转录激活因子5b（STAT5b）缺陷型小鼠的结肠基因差异表达情况。关键词：野生型及STAT5b缺陷型小鼠的单时间点样本。本实验从成年野生型及STAT5b缺陷型小鼠体内分离得到结肠RNA。