Evaluation of the impact of aging on lung tumor progression
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE277408
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To understand the impact of aging on lung tumor progression, we isolated lung tumor cells from Kras LSL-G12D/+; Trp53 fl/fl (KP) mouse models at different stage of tumor progression and performed single-cell sequencing on them. Aged (> 2 years old) and young (12-16 weeks old) Kras LSL-G12D/+; Trp53 fl/fl (KP) mouse models with or without reporter alleles were infected by adenoviral Cre recombinase and tumor cells at different tumor development were isolated for single-cell mRNA sequencing
创建时间:
2024-09-19



