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Small molecules enable highly efficient neuronal conversion of human fibroblasts

ChEBI2012-04-07 更新2026-07-21 收录

细胞重编程

神经再生

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-36246 数据链接链接失效反馈

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Small molecules enable highly efficient neuronal conversion of human fibroblasts

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创建时间：

2012-04-07

细胞重编程

心肌细胞去分化机制

In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BI

NIAID Data Ecosystem50

Additional file 5 of Unraveling the 2,3-diketo-l-gulonic acid-dependent and -independent impacts of l-ascorbic acid on somatic cell reprogramming

细胞重编程

维生素C生化作用

Additional file 5: Table S4. Reagents and resources used in the current studies.

NIAID Data Ecosystem40

Misdirection of axonal outgrowth of nerve fibers after nerve injury and repai...

神经再生

轴突导向机制

Peripheral nerve injuries are common and lead to life-long disability for affected individuals in spite of surgical treatments. Yet an unsolved clinical problem is misdirected...

B2FIND20

Comparison of hiPSCs, hESCs and fibroblasts

细胞重编程

基因表达谱比较分析

In our study, PRDM14 and NFRkB were found to enhance the reprogramming of human fibroblasts to hiPSCs in the presence of OCT4, SOX2, KLF4, with/without c-MYC (OSK/OSKC). To examnie if the obtained hiP

NIAID Data Ecosystem50

Chemical-based external stimulation reprograms BJs into FiNs (bulk RNA-seq)

细胞重编程

转录组学分析

Here, we report that chemical-based external stimulation reprograms human BJs to generate human induced FiNs. Using transcriptome,and chromatin accessibility, we identified the cells exhibited key fe

NIAID Data Ecosystem20

Small molecules enable highly efficient neuronal conversion of human fibroblasts

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