Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine ligand
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Crystal structure of the BCL6 BTB domain in complex with pyrazolo-pyrimidine ligand Descriptor: B-cell lymphoma 6 protein, ~{N}-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[(3~{R})-3-(dimethylamino)pyrrolidin-1-yl]phenyl]ethanamide Authors: Robb, G, Ferguson, A, Hargreaves, D. Deposit date: 2017-02-06 Release date: 2017-05-17 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors. J. Med. Chem., 60, 2017
创建时间：
2017-02-06
