SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors. SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors

NIAID Data Ecosystem2026-03-10 收录

化疗耐药机制

BRAF突变肺癌

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA495756 数据链接链接失效反馈

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资源简介：

We performed RNA sequencing analysis using NextSeq500 to identify drivers that mediate feedback RAS activation in BRAF(V600E) cells that are SHP2 independent. Overall design: mRNA expression of three BRAF (V600E) cancer cells was examined before and after treatment with vemurafenib (RAF inhibitor) using NextSeq500

创建时间：

2018-10-11