Enantioselective NHC-Catalyzed Redox [4 + 2]-Hetero-Diels–Alder Reactions Using α,β-Unsaturated Trichloromethyl Ketones as Amide Equivalents
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接：
https://figshare.com/articles/dataset/Enantioselective_NHC_Catalyzed_Redox_4_2_Hetero_Diels_Alder_Reactions_Using_Unsaturated_Trichloromethyl_Ketones_as_Amide_Equivalents/2126242
下载链接
链接失效反馈官方服务：
资源简介：
α,β-Unsaturated
trichloromethyl ketones are suitable
α,β-unsaturated amide and ester equivalents in N-heterocyclic
carbene (NHC)-catalyzed redox hetero-Diels–Alder reactions
with azolium enolates generated from α-aroyloxyaldehydes. The
initially formed syn-dihydropyranone products can
be isolated or can undergo ring-opening with benzylamine followed
by aminolysis of the resulting CCl3 ketone to form a range
of diamides with high diastereo- and enantioselectivity (up to >95:5
dr and >99% ee).
创建时间：
2016-02-13
