Association statistics and effects of 203 genome-wide significant SNPs

For each SNP, the mat file contains the RSID, chromosome and hg19 position, canonical correlation values, CCA coefficients, meta-analysis p-values, degrees of freedom, the p-value from the CCA step, and the p-value from the regression of slopes. Values from the US-driven meta-analysis are in the first column and values from the UK-driven meta-analysis are in the second column. For each SNP, the pdf file contains: (A) -log10(p-value) of the meta-analysis p-values per facial segment in METAUS and METAUK. Black-encircled facial segments have reached a genome-wide p-value (p -8). (B) The normal displacement (displacement in the direction locally normal to the facial surface) in each quasi-landmark of the facial segment reaching the lowest p-value in METAUS and METAUK going from the minor to the major allele SNP variant. Blue: inward depression; Red: outward protrusion. (C) LocusZoom plots in METAUK (top) and METAUS (bottom). Points are color-coded based on linkage disequilibrium (r2) in the 1000G Phase 3 EUR super-population. Asterisks represent genotyped SNPs, circles represent imputed SNPs.