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Microarray Analyses of mRNA in lncRNA IRENA overexpressed macrophages

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE134599
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LncRNAs play a critical role in both innate and adaptive immunity by regulating survival, differentiation, migration and cytokine production of the immune cells We found a cytoplasmic lncRNA IRENA in the TAMs, which triggered the NF-κB signaling and increased the production of pro-tumor inflammatory cytokines. We comparied mRNA expression profile of IRENA overexpressed macrophages with vector group.
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2021-06-12
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