Transcriptomic Response of a Model Melanoma to Probiotic Bacteria
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1214537
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资源简介：
This study investigated the strain-specific effects of Bifidobacterium adolescentis 150 and Lacticaseibacillus rhamnosus K32 on the transcriptional landscape of B16-F1 murine melanoma cells. Bulk RNA-seq analysis revealed distinct, strain-dependent alterations in gene expression profiles, suggesting species-specific immunomodulatory or metabolic interactions between probiotics and melanoma. These findings provide insights into microbial-tumor crosstalk and potential therapeutic avenues. Financial support for this study was provided by the Russian Science Foundation under the grant #22-75-10029 (https://rscf.ru/project/22-75-10029/).
创建时间：
2025-01-23
