Table 1 from Coevolution of Atypical BRAF and KRAS Mutations in Colorectal Tumorigenesis

Clinicopathologic and molecular summary information for BRAF-mutant patients in the combined cohort, stratified by functional classes 1, 2, and 3. The presence of concomitant pathogenic mutations in KRAS, NRAS, or NF1 is shown for each class. In addition to the data in the table, a single instance of co-occurring class 2 and 3 BRAF mutations was found. Unclassified mutations are assumed to be passenger changes for the purpose of our analysis. WT BRAF colorectal cancers within the combined cohort are included for reference. Percentages shown in parentheses reflect the proportion of total samples with available data for a given variable.