Genome-wide map of GATA6 DNA binding in human CRC cells
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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资源简介:
We describe the genome-wide DNA-binding of GATA6 in a human CRC cell line (LS174T). GATA6 is found to bind the promoter of genes involved in the maintenance of intestinal stem cells, including genes of the Wnt and TGFbeta/BMP pathways. With this we describe a novel GATA6-dependent mechanism of stem cell maintenance in colorectal tumors.
提供机构:
IRB Barcelona
创建时间:
2022-02-20



