Percent changes (Δ-values are differences between means) in protein levels and proteolytic activity of Separase after IM treatment when compared to corresponding untreated cells.

1 Δ-values were calculated from significant data sets diagrammed in Fig 1. All values are normalized to Actin.
2 for representative corresponding immunostained Western blots see Fig 1.
3 calculated quotient of Separase proteolytic activity [%] / Separase protein level [%]. Example (K526): (100+9.1)/(100–56.9) = 2.5
Abbreviations: d, days; h, hours; IM, imatinib; +, increase;-, decrease.
The confidence interval (95%CI) is given in parentheses.
** Since the CI of the denominator includes zero, it is not possible to compute the CI of this quotient.
Percent changes (Δ-values are differences between means) in protein levels and proteolytic activity of Separase after IM treatment when compared to corresponding untreated cells.