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Parallel characterization of cis-Regulatory Elements for Multiple Genes using CRISPRpath [Cut&Tag]

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NIAID Data Ecosystem2026-03-12 收录
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Here, we describe CRISPRpath, a CRISPR screening strategy for simultaneously characterizing CREs in multiple genomic loci by leveraging converging phenotypes resulted from transcriptional defects in genes linked to the same biological pathway. Overall design: Examination of histone modification (H3K4me3) and transcription factor binding (CTCF) in WTC11 human iPSCs.

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2021-09-30
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