Research Data supporting "Age and an obesogenic diet affect mouse behaviour in a sex-dependent manner"

There are three variables: age (8-9 weeks, 11-13 weeks and 20-22), sex, and diet (control or high fat, high sugar).

There are three types of data:
1. Behaviour (open field OF, elevated plus maze EPM or social preference SP tasks): effects of age (OF and EPM only), sex and diet
2. Nutrient intake: food intake, calorie intake and protein intake
3. Body composition: body weight, total body fat mass and individual fat deposit masses.

All three types of data are in CSV files.
1. Behavioural data: these are structured by sex and either age (Figure 1, OF; Figure 2, EPM) or by diet (OF, Figure 5; EPM, Figure 6; SP, Figure 7). For OF data, measurements include the total number of lines crossed in the OF, the number of entries into the centre of the OF, the time spent in the centre of the OF (in seconds) and the number of times the mouse rears within the OF. For EPM data, measurements include the time spent in the open arm of the EPM (% of total), the number of full entries to the open arm, the number of full entries to the closed arm, the number of explorations to the end of the open arm, and the number of times the mouse rears in the open arm. For SP data, measurements include the time spent in the intruder compartment as a % of total time and the social preference index (TS-TNS)/(TS+TNS), where TS is the social stimulus or intruder mouse and TNS is the non-social stimulus or object.
2. Nutrient intake is expressed as either kcal or g of food or protein per day per gram of mouse, measured weekly over a 24h period from weeks 9-13 for a subset of cages. There is a single CSV file containing the data for male and female mice on either the standard lab chow or on the high fat, high sugar diet.
3. Body composition: total body fat and lean mass (measured by Dual Energy X-ray Absorptiometry (DEXA) scanning (Lunar PIXImus densitometer; GE Healthcare) and/or the weights of the individual fat deposits and body organs are expressed in grams. There is a single CSV file containing the data for male and female mice on either the standard lab chow or on the high fat, high sugar diet.

本数据集包含三个变量：年龄（8-9周、11-13周及20-22周）、性别以及饮食（对照组或高脂、高糖饮食）。数据类型分为以下三种：

1. 行为数据（开放场OF、升高加迷宫EPM或社会偏好SP任务）：年龄（仅OF和EPM）、性别和饮食对行为的影响
2. 营养摄入：食物摄入量、卡路里摄入量和蛋白质摄入量
3. 体质成分：体重、全身脂肪总量及个体脂肪沉积量。

所有三种类型的数据均以CSV文件格式存储。
1. 行为数据：数据按性别和年龄（图1，OF；图2，EPM）或饮食（OF，图5；EPM，图6；SP，图7）进行结构化。对于OF数据，测量指标包括开放场中穿过的总线条数、进入开放场中心的次数、在开放场中心停留的时间（以秒计）以及小鼠在开放场中竖起背部的次数。对于EPM数据，测量指标包括在EPM开放臂中度过的时间（占总时间的百分比）、进入开放臂的完整次数、进入封闭臂的完整次数、探索开放臂末端的次数以及小鼠在开放臂中竖起背部的次数。对于SP数据，测量指标包括在入侵者隔间中度过的时间占总时间的百分比以及社会偏好指数（TS-TNS）/（TS+TNS），其中TS为社会刺激或入侵小鼠，TNS为非社会刺激或物体。
2. 营养摄入以每克小鼠每天的食物或蛋白质的卡路里（kcal）或克（g）表示，每周测量一次，持续24小时，时间为第9-13周的部分笼子。存在一个包含雄性和雌性小鼠在标准实验室饲料或高脂、高糖饮食上的数据的单独CSV文件。
3. 体质成分：全身脂肪和瘦体重（通过双能量X射线吸收法（DEXA）扫描（Lunar PIXImus densitometer；GE Healthcare）和/或个体脂肪沉积和身体器官的重量测量，并以克为单位表示）。存在一个包含雄性和雌性小鼠在标准实验室饲料或高脂、高糖饮食上的数据的单独CSV文件。